Flexeril Uses, Dosage, Side Effects & Warnings

Avoid taking MAO inhibitors (isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with this medication. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Overdose symptoms may include severe drowsiness, vomiting, fast heartbeats, tremors, agitation, or hallucinations. Analysis of the data from controlled studies shows that FLEXERIL produces clinical improvement whether or not sedation occurs. In patients with CNS depression, early intubation is advised because of the potential for abrupt deterioration. Seizures should be controlled with benzodiazepines or, if these are ineffective, other anticonvulsants (e.g. phenobarbital, phenytoin).

Before taking cyclobenzaprine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. This is not a complete list of side effects and others may occur. Take this medication by mouth with or without food as directed by your doctor, usually once daily. Doing so can release all of the drugs at once, increasing the risk of side effects. The efficacy of FLEXERIL 5 mg was demonstrated in two seven-day, double-blind, controlled clinical trials enrolling 1405 patients.

• For most patients, the recommended starting dose is 5 mg three times a day.
• Do not take this drug again if you’ve ever had an allergic reaction to it.
• Because cyclobenzaprine is closely related to the tricyclic antidepressants, some of which are known to be excreted in human milk, caution should be exercised when FLEXERIL is administered to a nursing woman.
• In a pharmacokinetic study of sixteen subjects with hepatic impairment (15 mild, 1 moderate per Child-Pugh score), both AUC and Cmax were approximately double the values seen in the healthy control group.
• Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

No data directly compares the two drugs in terms of pain relief. American Family Physician states that there is weak (and very little) evidence in terms of muscle relaxants and their efficacy compared to each other. They recommend that the selection of a muscle relaxant should be based on the potential for side effects, drug interactions, abuse, and also patient preference.

Call your doctor or local poison control center immediately if you have an allergic reaction. Call 911 or go to the nearest emergency room if your symptoms are severe. Do not take this drug again if you’ve ever had an allergic reaction to it. Cyclobenzaprine belongs to a class of drugs called muscle relaxants.

Flexeril (Generic Cyclobenzaprine)

If you have muscle spasms or muscle pain and plan to take skeletal muscle relaxants, please work with your healthcare provider to find the one that works best for you. Keep in mind that along with medications for short-term alleviation of pain and discomfort, rest and physical therapy can help with long-term pain relief and function. Drug interactions may change how your how strong is flexeril medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

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Some people prefer Fexmid and Amrix over Robaxin because it is dosed once a day rather than 3 to 4 times a day. On the other hand, they can cause more adverse effects such as dry mouth and drowsiness. When certain drugs are used with cyclobenzaprine, they may cause more severe side effects such as increased drowsiness or sedation. A person should ask their doctor whether it is safe to combine another medication with cyclobenzaprine and take care not to operate any machinery while taking it. To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking.

Does Skelaxin help with pain?

A class of drugs is a group of medications that work in a similar way. Cyclobenzaprine is used short-term to treat muscle spasms. Yes, cyclobenzaprine can make you very sleepy and this side effect may get worse with higher doses.

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Tell your doctor about any other medications you are currently using in order to reduce the risk of interactions. Talk to your doctor if you are pregnant or breastfeeding to discuss any possible risks. Avoid driving or operating heavy machinery until you know how this medication affects you, as your reactions could be impaired. If you experience any serious side effects or signs of an allergic reaction, seek emergency medical attention.

What Are Dosages of Cyclobenzaprine?

Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Check with your physician if you have health questions or concerns. Concomitant use of monoamine oxidase (MAO) inhibitors or within 14 days after their discontinuation. Hyperpyretic crisis seizures, and deaths have occurred in patients receiving cyclobenzaprine (or structurally similar tricyclic antidepressants) concomitantly with MAO inhibitor drugs. Cyclobenzaprine is a centrally acting muscle relaxant closely related to the tricyclic antidepressants. Despite its similarity to tricyclic antidepressants, there is little evidence that cyclobenzaprine causes liver injury.

Ask your doctor when to start or stop taking this medication. Cyclobenzaprine starts to relax muscles and relieve muscle spasms about an hour after it is ingested. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company. Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness.